Biostimulators vs. Fillers: What’s the Difference?

At Belle Jeunesse, one of the most common questions we hear is: “What’s the difference between a filler and a biostimulator?” Both treatments restore a youthful look, but they work in very different ways. Understanding the difference helps you make the best choice for your goals.

What Are Dermal Fillers?

Dermal fillers are injectable gels, most often made from hyaluronic acid (HA) — a substance your body naturally produces to keep skin plump and hydrated.

How They Work

• Instantly add volume under the skin.
• Fill wrinkles, folds, or hollow areas (like cheeks or under-eyes).
• Results are visible immediately after treatment.

Popular Uses

• Lip enhancement
• Cheekbone definition
• Nasolabial folds (smile lines)
• Under-eye hollows
• Jawline contouring

Longevity

• Results typically last 6–12 months, depending on product and area treated.
• Fillers can be dissolved if needed, giving flexibility.

What Are Biostimulators?

Biostimulators, such as Radiesse®, Sculptra®, and EZ Gel PRF, don’t simply “fill.” Instead, they stimulate your body to produce more collagen and elastin over time.

How They Work

• Trigger your skin’s natural healing response.
• Improve thickness, elasticity, and overall quality.
• Results build gradually and look very natural.

Popular Uses

• Global facial rejuvenation
• Jawline and cheek contour
• Temples and areas of volume loss
• Skin tightening and texture improvement
• Long-lasting under-eye or midface support with PRF/EZ Gel

Longevity

• Results can last 18–24 months or more.
• Improvements are gradual but long-lasting.

Key Differences

• Fillers = Immediate results (like inflating a balloon).
• Biostimulators = Long-term collagen production (like planting seeds that grow over time).
• Fillers are best for quick correction and contouring.
• Biostimulators are best for global rejuvenation and skin quality.

Which One Is Right for You?

At Belle Jeunesse, many patients actually benefit from a combination of both:

• Fillers for instant lift and definition.
• Biostimulators for long-term collagen and natural support.

During your consultation, Dr. Karimkhani and our team will evaluate your skin, facial structure, and goals to recommend the most effective approach.

Belle Jeunesse Contact

Whether you’re looking for instant refreshment or long-term rejuvenation, we’ll help you find the right treatment plan. Call 949-545-8367 to schedule your consultation today.